- Andre Braugher as Captain Marcus Chaplin
- Daisy Betts as Lieutenant Grace Shepard
- Daniel Lissing
- Autumn Reeser as Kylie Sinclair
- Scott Speedman as XO Sam Kendal
- Camille De Pazzis
- Sahr Ngaujah
- Dichen Lachman as Tani Tumrenjack
- Jessy Schram
- Robert Patrick as Master Chief Joseph Prosser
500 feet beneath the ocean's surface, the U.S. ballistic missile submarine Colorado receive their orders. Over a radio channel, designed only to be used if their homeland has been wiped out, they're told to fire nuclear weapons at Pakistan.
Captain Marcus Chaplin (Andre Braugher) demands confirmation of the orders only to be unceremoniously relieved of duty by the White House. XO Sam Kendal (Scott Speedman) finds himself suddenly in charge of the submarine and facing the same difficult decision. When he also refuses to fire without confirmation of the orders, the Colorado is targeted, fired upon, and hit. The submarine and its crew find themselves crippled on the ocean floor, declared rogue enemies of their own country. Now, with nowhere left to turn, Chaplin and Kendal take the sub on the run and bring the men and women of the Colorado to an exotic island. Here they will find refuge, romance and a chance at a new life, even as they try to clear their names and get home.